Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 5/20 | 0.61 |
| ▸ | FABP3 | P05413 | 2/20 | 0.57 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.54 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | DHFR | P00374 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL355549 | 0.84 | FABP4 (0.80) | FABP4FABP3FABP5AKR1C3AKR1C2 | |
| SCHEMBL30320327 | 0.84 | FABP4 (0.80) | FABP4FABP3FABP5AKR1C3AKR1C2 | |
| SCHEMBL27703496 | 0.84 | FABP4 (0.59) | FABP4FABP3FABP5AKR1C3AKR1C2 | |
| SCHEMBL6142375 | 0.82 | FABP4 (0.84) | FABP4FABP3FABP5AKR1C3AKR1C2 | |
| SCHEMBL9691899 | 0.82 | FABP4 (0.77) | FABP4FABP3FABP5AKR1C3AKR1C2 | |
| SCHEMBL4333864 | 0.82 | LMNA (0.60) | MEN1LMNACYP1A2CYP2C9KMT2A | |
| SCHEMBL7527736 | 0.81 | FABP4 (0.56) | FABP4FABP3FABP5AKR1C3AKR1C2 | |
| SCHEMBL7029629 | 0.81 | MAPT (0.61) | PTGS2LMNACYP1A2KMT2ATDP1 | |
| SCHEMBL20448823 | 0.78 | ALDH1A1 (0.59) | AKR1C3MEN1LMNACYP1A2CYP2C9 | |
| SCHEMBL29556927 | 0.78 | ALDH1A1 (0.59) | AKR1C3MEN1LMNACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997027179-A2 | ANTIRETROVIRAL BASES | NOVARTIS AG (CH) | 1997-07-31 | — | — | WO | disclosed |