Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | JAK2 | O60674 | 1/20 | 0.55 |
| ▸ | ATIC | P31939 | 1/20 | 0.55 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.48 |
| ▸ | MEN1 | O00255 | 7/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1414326 | 0.79 | LMNA (0.78) | LMNACYP2C9KDM4EATICPDGFRB | |
| SCHEMBL30517293 | 0.79 | LMNA (0.78) | LMNACYP2C9KDM4EATICPDGFRB | |
| SCHEMBL3447749 | 0.78 | ALDH1A1 (0.59) | LMNACYP2C9KDM4EHSP90AA1HSP90AB1 | |
| SCHEMBL15256346 | 0.78 | LMNA (0.74) | LMNACYP2C9KDM4EATICKMT2A | |
| SCHEMBL5780177 | 0.77 | PDGFRB (0.62) | LMNACYP2C9KDM4EHSP90AA1HSP90AB1 | |
| SCHEMBL8892993 | 0.75 | MEN1 (0.46) | LMNACYP2C9KDM4EKMT2AMEN1 | |
| Sulfaquinoxaline SCHEMBL93789 | 0.74 | LMNA (1.00) | LMNACYP2C9KDM4EATICKMT2A | |
| Sulfaquinoxaline SCHEMBL4435622 | 0.74 | LMNA (1.00) | LMNACYP2C9KDM4EATICKMT2A | |
| Sulfaquinoxaline SCHEMBL29391090 | 0.74 | LMNA (1.00) | LMNACYP2C9KDM4EATICKMT2A | |
| SCHEMBL1385573 | 0.74 | LMNA (0.66) | LMNACYP2C9KDM4EHSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997032858-A1 | QUINOXALINE DERIVATIVES AS GLUTAMATE RECEPTOR ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-12 | — | — | WO | disclosed |