Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 10/20 | 0.44 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.42 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.42 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.42 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MLNR | O43193 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9040006 | 0.80 | GUCY1B2 (0.46) | MEN1KMT2AGUCY1B2GUCY1A2GUCY1A1 | |
| SCHEMBL11263318 | 0.79 | ALDH1A1 (0.44) | MEN1KMT2AGUCY1B2GUCY1A2GUCY1A1 | |
| SCHEMBL7356089 | 0.75 | CYP1A2 (0.58) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL1551650 | 0.75 | SMN1; SMN2 (0.50) | MEN1KMT2AGUCY1B2GUCY1A2GUCY1A1 | |
| SCHEMBL8892306 | 0.75 | GUCY1B2 (0.50) | MEN1KMT2ACYP19A1GUCY1B2GUCY1A2 | |
| SCHEMBL8892404 | 0.75 | LMNA (0.59) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL3720824 | 0.73 | ALDH1A1 (0.50) | MEN1KMT2AGUCY1B2GUCY1A2GUCY1A1 | |
| SCHEMBL9703345 | 0.73 | LMNA (0.69) | MEN1KMT2AKDM4ELMNACYP2C9 | |
| SCHEMBL30891041 | 0.72 | ALDH1A1 (0.49) | MEN1KMT2AGUCY1B2GUCY1A2GUCY1A1 | |
| SCHEMBL3567491 | 0.72 | ALDH1A1 (0.49) | MEN1KMT2AGUCY1B2GUCY1A2GUCY1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997032858-A1 | QUINOXALINE DERIVATIVES AS GLUTAMATE RECEPTOR ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-12 | — | — | WO | disclosed |