Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.32 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.32 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.32 |
| ▸ | SLC8A1 | P32418 | 1/20 | 0.32 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892376 | 0.91 | NPC1 (0.36) | NPC1RAB9APOLBSMN1; SMN2GAA | |
| SCHEMBL8892248 | 0.90 | ALDH1A1 (0.35) | POLBSMN1; SMN2LMNAMAPK1ALDH1A1 | |
| SCHEMBL8890057 | 0.89 | NPC1 (0.37) | NPC1RAB9APOLBSMN1; SMN2GAA | |
| SCHEMBL8890655 | 0.86 | LMNA (0.46) | NPC1RAB9APOLBSMN1; SMN2GAA | |
| SCHEMBL8893258 | 0.85 | ALDH1A1 (0.47) | NPC1RAB9APOLBSMN1; SMN2GAA | |
| SCHEMBL8891787 | 0.85 | HTT (0.35) | GAALMNAALDH1A1PKMKMT2A | |
| SCHEMBL8894341 | 0.84 | L3MBTL1 (0.42) | POLBLMNAALDH1A1PKMKMT2A | |
| SCHEMBL8891930 | 0.84 | ALDH1A1 (0.40) | NPC1RAB9APOLBSMN1; SMN2GAA | |
| SCHEMBL8890386 | 0.82 | LMNA (0.35) | RAB9APOLBSMN1; SMN2GAALMNA | |
| SCHEMBL8891118 | 0.81 | ALDH1A1 (0.36) | POLBSMN1; SMN2LMNAMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607976-A | ANNTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |