Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.33 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.33 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890064 | 0.91 | L3MBTL1 (0.43) | L3MBTL1TSHRPOLBHPGDALDH1A1 | |
| SCHEMBL8892035 | 0.90 | LMNA (0.33) | L3MBTL1TSHRPOLBALDH1A1LMNA | |
| SCHEMBL8890328 | 0.88 | L3MBTL1 (0.43) | L3MBTL1TSHRPOLBHPGDALDH1A1 | |
| SCHEMBL8891470 | 0.86 | ABCC9 (0.47) | L3MBTL1TSHRPOLBPKMLMNA | |
| SCHEMBL8891787 | 0.85 | HTT (0.35) | HPGDALDH1A1MAPTPKMLMNA | |
| SCHEMBL8892423 | 0.84 | NPC1 (0.35) | POLBALDH1A1PKMLMNAKMT2A | |
| SCHEMBL8890853 | 0.84 | L3MBTL1 (0.41) | L3MBTL1TSHRPOLBHPGDALDH1A1 | |
| SCHEMBL8892350 | 0.84 | ABCC9 (0.33) | HPGDALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL8891256 | 0.83 | KDM4E (0.34) | HPGDALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL8893925 | 0.83 | L3MBTL1 (0.40) | L3MBTL1TSHRPOLBHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607976-A | ANNTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |