Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 7/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 5/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892614 | 0.90 | HPGD (0.43) | F10ITGB3PRSS1PRSS2ITGA2B | |
| SCHEMBL7463621 | 0.88 | NAMPT (0.38) | F10ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL8892115 | 0.86 | NAMPT (0.37) | F10ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7464219 | 0.83 | SIGMAR1 (0.41) | F10LMNAMEN1KMT2ANAMPT | |
| Water SCHEMBL7461996 | 0.83 | SIGMAR1 (0.41) | F10LMNAMEN1KMT2ANAMPT | |
| SCHEMBL7458570 | 0.83 | NAMPT (0.43) | F10ITGB3PRSS1PRSS2ITGA2B | |
| SCHEMBL7462288 | 0.82 | LMNA (0.40) | LMNAMEN1KMT2ANAMPTTP53 | |
| SCHEMBL7456463 | 0.81 | ITGB3 (0.49) | F10ITGB3PRSS1PRSS2ITGA2B | |
| Ether SCHEMBL7461990 | 0.80 | SIGMAR1 (0.39) | F10ITGB3PRSS1PRSS2ITGA2B | |
| SCHEMBL8892340 | 0.80 | MEN1 (0.42) | ITGB3ITGA2BMEN1KMT2ANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614535-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |