Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.37 |
| ▸ | CCR3 | P51677 | 2/20 | 0.37 |
| ▸ | ADH1B | P00325 | 2/20 | 0.37 |
| ▸ | ADH1C | P00326 | 2/20 | 0.37 |
| ▸ | ADH1A | P07327 | 2/20 | 0.37 |
| ▸ | ADH7 | P40394 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7832303 | 0.94 | CCR1 (0.37) | CCR1CCR3ADH1BADH1CADH1A | |
| SCHEMBL7823386 | 0.86 | ADH1B (0.38) | CCR1CCR3ADH1BADH1CADH1A | |
| SCHEMBL7822809 | 0.84 | CCR3 (0.37) | CCR1CCR3ADH1BADH1CADH1A | |
| SCHEMBL8894063 | 0.84 | ADH1B (0.37) | ADH1BADH1CADH1AADH7ALDH1A1 | |
| SCHEMBL8893131 | 0.81 | CCR1 (0.35) | CCR1CCR3ADH1BADH1CADH1A | |
| SCHEMBL7816549 | 0.79 | CCR3 (0.45) | CCR1CCR3HTTLMNASMN1; SMN2 | |
| SCHEMBL7817246 | 0.78 | ADH1B (0.37) | ADH1BADH1CADH1AADH7ALDH1A1 | |
| SCHEMBL7830626 | 0.77 | L3MBTL1 (0.49) | CCR1CCR3KDM4EHTTPOLB | |
| SCHEMBL7827029 | 0.76 | KIF11 (0.47) | CCR1CCR3MAPTKDM4EALDH1A1 | |
| SCHEMBL8315609 | 0.76 | ADH1B (0.40) | CCR1CCR3ADH1BADH1CADH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997024325-A1 | DIPHENYLMETHANE DERIVATIVES AS MIP-1α/RANTES RECEPTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-07-10 | — | — | WO | disclosed |