Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890162 | 0.89 | KMT2A (0.53) | KMT2AMAPK1HPGDMAPTALDH1A1 | |
| SCHEMBL4315767 | 0.82 | PKM (0.46) | KMT2AMAPK1HPGDMAPTALDH1A1 | |
| SCHEMBL8891792 | 0.82 | TSHR (0.63) | KMT2AMAPK1MAPTTHRBALDH1A1 | |
| SCHEMBL8889779 | 0.80 | PDE4D (0.61) | KMT2AMAPK1ALDH1A1MEN1CYP1A2 | |
| SCHEMBL4320922 | 0.79 | PKM (0.67) | KMT2AHPGDMAPTALDH1A1MEN1 | |
| SCHEMBL8890403 | 0.77 | SYK (0.57) | KMT2AMAPTALDH1A1MEN1KDM4E | |
| SCHEMBL31482053 | 0.77 | ALDH1A1 (0.51) | KMT2AHPGDMAPTTHRBALDH1A1 | |
| SCHEMBL13141043 | 0.76 | IDO1 (0.57) | KMT2AHPGDMAPTTHRBALDH1A1 | |
| SCHEMBL8890420 | 0.75 | HIF1A (0.55) | KMT2AHPGDMAPTTHRBALDH1A1 | |
| SCHEMBL31172625 | 0.75 | KMT2A (0.48) | KMT2AHPGDMAPTTHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997003967-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND THEIR PHARMACEUTICAL USE | RHONE-POULENC RORER LIMITED (GB) | 1997-02-06 | — | — | WO | disclosed |