Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892297 | 0.89 | RXRA (0.54) | SMPD1HDAC1HDAC8HDAC6HPGD | |
| SCHEMBL8890381 | 0.86 | NPC1 (0.49) | SMPD1HDAC1HDAC8HDAC6HPGD | |
| SCHEMBL8891792 | 0.82 | TSHR (0.63) | HIF1ALMNAMAPTTHRBSMN1; SMN2 | |
| SCHEMBL9233919 | 0.81 | TSHR (0.62) | HPGDLMNAMAPTSMN1; SMN2NPC1 | |
| SCHEMBL2188210 | 0.81 | SMPD1 (0.76) | SMPD1HDAC1HDAC8HDAC6HPGD | |
| SCHEMBL2063068 | 0.81 | SMN1; SMN2 (0.73) | SMPD1HDAC1HDAC8HDAC6HPGD | |
| SCHEMBL8891413 | 0.80 | ALDH1A1 (0.55) | HIF1AHPGDLMNAMAPTTHRB | |
| SCHEMBL6667451 | 0.80 | LOXL2 (0.64) | HIF1AHPGDLMNAMAPTSMN1; SMN2 | |
| SCHEMBL13141043 | 0.79 | IDO1 (0.57) | HIF1AHPGDMAPTTHRBSMN1; SMN2 | |
| SCHEMBL28881534 | 0.78 | LMNA (0.48) | SMPD1HDAC1HDAC8HDAC6HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997003967-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND THEIR PHARMACEUTICAL USE | RHONE-POULENC RORER LIMITED (GB) | 1997-02-06 | — | — | WO | disclosed |