Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP24A1 | Q07973 | 2/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | PSMD10 | O75832 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19922717 | 0.83 | PSMD10 (0.43) | CYP24A1STAT3PSMD10CA12CA9 | |
| SCHEMBL8312617 | 0.83 | CYP24A1 (0.37) | CYP24A1STAT3PSMD10CA12CA9 | |
| SCHEMBL7827075 | 0.79 | ENPP3 (0.36) | CYP24A1STAT3PSMD10ALDH1A1MEN1 | |
| SCHEMBL16771628 | 0.78 | ALDH1A1 (0.45) | STAT3PSMD10CA12CA9CA1 | |
| SCHEMBL28719294 | 0.76 | CYP24A1 (0.42) | CYP24A1STAT3PSMD10CA12CA9 | |
| SCHEMBL912590 | 0.75 | CYP24A1 (0.40) | CYP24A1STAT3HTR1APSMD10CA12 | |
| SCHEMBL22945668 | 0.75 | CYP24A1 (0.41) | CYP24A1STAT3CA12CA9CA1 | |
| SCHEMBL6005376 | 0.74 | KIF11 (0.47) | CYP24A1STAT3CA12CA9CA1 | |
| SCHEMBL24488898 | 0.73 | CYP24A1 (0.40) | CYP24A1STAT3PSMD10CA12CA9 | |
| SCHEMBL31516447 | 0.72 | TK1 (0.46) | CYP24A1STAT3ALDH1A1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997024325-A1 | DIPHENYLMETHANE DERIVATIVES AS MIP-1α/RANTES RECEPTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-07-10 | — | — | WO | disclosed |