Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 6/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 6/20 | 0.34 |
| ▸ | F10 | P00742 | 4/20 | 0.34 |
| ▸ | CTSV | O60911 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7462601 | 0.92 | PRSS1 (0.41) | SMN1; SMN2CYP2C19GRM2PDE4BNPC1 | |
| SCHEMBL8892948 | 0.88 | SMN1; SMN2 (0.44) | SMN1; SMN2CYP2C19NPC1RAB9AHPGD | |
| SCHEMBL7517993 | 0.85 | L3MBTL1 (0.40) | SMN1; SMN2GRM2NPC1RAB9ACTSL | |
| SCHEMBL8893028 | 0.84 | ITGB3 (0.43) | SMN1; SMN2CYP2C19GRM2KCNH2HPGD | |
| SCHEMBL7462288 | 0.80 | LMNA (0.40) | PDE4BGPR119 | |
| SCHEMBL8894267 | 0.79 | PRSS1 (0.51) | SMN1; SMN2CYP2C19NPC1RAB9AHPGD | |
| SCHEMBL8893356 | 0.78 | SMN1; SMN2 (0.42) | SMN1; SMN2CYP2C19NPC1RAB9AHPGD | |
| SCHEMBL8316057 | 0.76 | PRSS1 (0.46) | GRM2ITGB3PRSS1PRSS2ITGA2B | |
| SCHEMBL8312993 | 0.76 | PRSS1 (0.46) | GRM2ITGB3PRSS1PRSS2ITGA2B | |
| SCHEMBL8313362 | 0.76 | PRSS1 (0.46) | GRM2ITGB3PRSS1PRSS2ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697408-B1 | 1 substituted-phenyl-oxazolidene-2-one derivatives and their use as adhesion-receptor antagonists | MERCK PATENT GMBH (DE) | 2002-01-23 | — | — | EP | disclosed |
| EP-0697408-A1 | 1 substituted-phenyl-oxazolidene-2-one derivatives and their use as adhesion-receptor antagonists | MERCK PATENT GmbH (DE) | 1996-02-21 | — | — | EP | disclosed |