Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892997 | 0.73 | ALDH1A1 (0.39) | KMT2AALDH1A1MAPTPKMTDP1 | |
| SCHEMBL9804350 | 0.67 | MEN1 (0.33) | KMT2AALDH1A1MEN1POLBGAA | |
| SCHEMBL18428973 | 0.66 | ALDH1A1 (0.45) | KMT2AALDH1A1MAPTPKMNPSR1 | |
| SCHEMBL10840973 | 0.65 | CHRM4 (0.35) | ALDH1A1NPSR1APPHPGDTSHR | |
| SCHEMBL5717885 | 0.64 | SIGMAR1 (0.45) | KMT2AALDH1A1USP2HSD17B10POLB | |
| Hydrochloric Acid SCHEMBL5849112 | 0.63 | SIGMAR1 (0.44) | KMT2AALDH1A1USP2HSD17B10POLB | |
| SCHEMBL27712800 | 0.61 | ELANE (0.37) | KMT2AALDH1A1NPSR1LMNAMEN1 | |
| SCHEMBL10839441 | 0.60 | PLA2G7 (0.40) | KMT2AALDH1A1NPSR1ALOX12MEN1 | |
| SCHEMBL204288 | 0.59 | NPSR1 (0.43) | KMT2AALDH1A1MAPTNPSR1MEN1 | |
| SCHEMBL8387202 | 0.59 | NPSR1 (0.43) | KMT2AALDH1A1MAPTNPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4981827-A | Catalysts | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-01 | — | — | US | disclosed |