Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | GALR2 | O43603 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PGK1 | P00558 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | GRM6 | O15303 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | GLP1R | P43220 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891999 | 0.83 | POLB (0.43) | POLBGALR2LMNAPGK1KDM4E | |
| SCHEMBL31530748 | 0.82 | LMNA (0.57) | POLBGALR2LMNAPGK1ALDH1A1 | |
| SCHEMBL8552936 | 0.82 | LMNA (0.57) | POLBGALR2LMNAPGK1ALDH1A1 | |
| SCHEMBL31530747 | 0.82 | LMNA (0.57) | POLBGALR2LMNAPGK1ALDH1A1 | |
| SCHEMBL8556955 | 0.77 | GAA (0.51) | POLBGALR2LMNAPGK1ALDH1A1 | |
| SCHEMBL1291907 | 0.77 | PGK1 (0.61) | POLBGALR2LMNAPGK1ALDH1A1 | |
| SCHEMBL5722727 | 0.74 | POLB (0.44) | POLBGALR2LMNAPGK1ALDH1A1 | |
| SCHEMBL8917176 | 0.73 | PGK1 (0.47) | POLBGALR2LMNAPGK1ALDH1A1 | |
| SCHEMBL19732138 | 0.72 | MAPT (0.46) | KDM4EALDH1A1HTTHCAR3MAPT | |
| SCHEMBL31425811 | 0.71 | HCAR3 (0.44) | LMNAKDM4EALDH1A1HTTHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997032858-A1 | QUINOXALINE DERIVATIVES AS GLUTAMATE RECEPTOR ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-12 | — | — | WO | disclosed |