Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 2/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9025606 | 0.88 | MGAM (0.39) | GPR84TACR1 | |
| SCHEMBL9026013 | 0.79 | NPC1 (0.36) | CYP1A2MEN1KMT2AKDM4E | |
| SCHEMBL9025431 | 0.76 | MEN1 (0.39) | GPR84CYP1A2MEN1KMT2AKDM4E | |
| SCHEMBL9025465 | 0.73 | CCR2 (0.34) | KDM4E | |
| SCHEMBL9025568 | 0.73 | METAP2 (0.39) | GPR84MEN1KMT2AKDM4E | |
| SCHEMBL9210152 | 0.73 | GPR84 (0.32) | GPR84 | |
| SCHEMBL9026040 | 0.71 | HTR2C (0.39) | MEN1KMT2A | |
| SCHEMBL9032014 | 0.71 | MAPT (0.36) | CYP1A2MEN1KMT2A | |
| SCHEMBL3983731 | 0.71 | SLC6A2 (0.37) | — | |
| SCHEMBL10919731 | 0.70 | KDM4E (0.36) | GPR84CYP1A2MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995004052-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1995-02-09 | — | — | WO | disclosed |