Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | BTN3A1 | O00481 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ENO1 | P06733 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 3/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL681950 | 0.87 | PRKCA (0.46) | PRKCABTN3A1ALDH1A1POLBGAA | |
| SCHEMBL4482845 | 0.83 | GAA (0.46) | PRKCABTN3A1ALDH1A1POLBGAA | |
| Bis(Pivaloyloxymethyl) Succinate SCHEMBL3123390 | 0.83 | PRKCA (0.41) | PRKCABTN3A1ALDH1A1POLBGAA | |
| SCHEMBL7338739 | 0.81 | NAAA (0.40) | PRKCABTN3A1ALDH1A1POLBGAA | |
| SCHEMBL8893364 | 0.81 | PRKCA (0.44) | PRKCABTN3A1ALDH1A1POLBGAA | |
| SCHEMBL434232 | 0.80 | PRKCA (0.42) | PRKCABTN3A1ALDH1A1POLBGAA | |
| SCHEMBL12842576 | 0.79 | PRKCA (0.38) | PRKCABTN3A1ALDH1A1POLBGAA | |
| SCHEMBL3835100 | 0.79 | DGKA (0.43) | PRKCABTN3A1ALDH1A1ELANE | |
| SCHEMBL10153884 | 0.78 | PRKCA (0.41) | PRKCABTN3A1ALDH1A1POLBGAA | |
| SCHEMBL8716409 | 0.78 | PRKCA (0.41) | PRKCABTN3A1ALDH1A1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643878-A | TREATMENT OF RETROVIRAL DISEASES LIKE AIDS | CIBA-GEIGY CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |
| EP-0618222-A2 | Dipeptid derivatives of 5-amino-4-hydroxy-hexanoic acid | CIBA-GEIGY AG (CH) | 1994-10-05 | — | — | EP | disclosed |