Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.33 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893347 | 1.00 | SMN1; SMN2 (0.39) | SMN1; SMN2CYP2C19NPC1RAB9AHPGD | |
| SCHEMBL8894573 | 0.85 | CYP1A2 (0.37) | SMN1; SMN2NPC1RAB9AMAPTHTT | |
| SCHEMBL8894594 | 0.85 | CYP1A2 (0.37) | SMN1; SMN2NPC1RAB9AMAPTHTT | |
| SCHEMBL8893356 | 0.78 | SMN1; SMN2 (0.42) | SMN1; SMN2CYP2C19NPC1RAB9AHPGD | |
| SCHEMBL8892948 | 0.76 | SMN1; SMN2 (0.44) | SMN1; SMN2CYP2C19NPC1RAB9AHPGD | |
| SCHEMBL8894267 | 0.76 | PRSS1 (0.51) | SMN1; SMN2CYP2C19NPC1RAB9AHPGD | |
| SCHEMBL8893479 | 0.76 | MAOA (0.33) | HTTPOLB | |
| SCHEMBL8890920 | 0.75 | L3MBTL1 (0.49) | SMN1; SMN2CYP2C19NPC1RAB9AHPGD | |
| SCHEMBL8893351 | 0.75 | HPGD (0.37) | SMN1; SMN2CYP2C19NPC1RAB9AHPGD | |
| SCHEMBL8893748 | 0.73 | HPGD (0.44) | SMN1; SMN2CYP2C19NPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614535-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |