Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 5/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
| ▸ | PYGL | P06737 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL645717 | 0.85 | LMNA (0.43) | MEN1KMT2AXIAPPYGL | |
| Hydrochloric Acid SCHEMBL645716 | 0.84 | LMNA (0.42) | MEN1KMT2AXIAPPYGL | |
| SCHEMBL5620305 | 0.78 | MEN1 (0.35) | MEN1KMT2AXIAP | |
| SCHEMBL5620313 | 0.78 | MEN1 (0.35) | MEN1KMT2AXIAP | |
| Hydrochloric Acid SCHEMBL4433659 | 0.77 | XIAP (0.34) | MEN1KMT2AXIAP | |
| Hydrochloric Acid SCHEMBL4433664 | 0.77 | XIAP (0.34) | MEN1KMT2AXIAP | |
| SCHEMBL4891481 | 0.76 | AADAT (0.59) | PDPK1ACEMMEPYGL | |
| SCHEMBL9698792 | 0.76 | TSHR (0.57) | CA12CA9MEN1KMT2A | |
| SCHEMBL8207671 | 0.75 | LMNA (0.38) | MEN1KMT2A | |
| SCHEMBL4434136 | 0.75 | GAA (0.51) | MEN1KMT2AXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677297-A | ENZYME INHIBITOR FOR TREATING THE HEART FAILURE TO REDUCE THE CARDIAC PRESSURE, DIURETICS | SOLVAY PHARMACEUTICALS GMBH (DE) | 1997-10-14 | — | — | US | disclosed |