Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | G6PD | P11413 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL949608 | 0.80 | ALDH1A1 (0.50) | HSP90AA1G6PDALDH1A1MAPTGAA | |
| SCHEMBL2155508 | 0.79 | ALDH1A1 (0.45) | HSP90AA1G6PDALDH1A1MAPTGAA | |
| SCHEMBL490330 | 0.77 | ALDH1A1 (0.62) | HSP90AA1G6PDALDH1A1MAPTGAA | |
| SCHEMBL12533795 | 0.73 | ALDH1A1 (0.49) | HSP90AA1G6PDALDH1A1MAPTGAA | |
| SCHEMBL1202896 | 0.71 | HSD17B10 (0.58) | G6PDALDH1A1MAPTLMNAHSD17B10 | |
| SCHEMBL439444 | 0.67 | G6PD (0.54) | G6PDMAPTLMNAHSD17B10 | |
| SCHEMBL37113 | 0.67 | — | — | |
| SCHEMBL5641989 | 0.67 | — | — | |
| SCHEMBL11184778 | 0.67 | ALDH1A1 (0.46) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL29289415 | 0.67 | ALDH1A1 (0.41) | HSP90AA1G6PDALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014170343-A1 | DEPOLARIZING AGENTS AND NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS FOR TREATING DOPAMINERGIC-RELATED DISORDERS | ICM (INSTITUT DU CERVEAU ET DE LA MOELLE ÉPINIÈRE) (FR) | 2014-10-23 | — | — | WO | disclosed |
| WO-1997019930-A1 | PROCESS FOR PRODUCING 1-AMINOHYDANTOIN | LONZA AG (CH) | 1997-06-05 | — | — | WO | disclosed |