Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 5/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27486662 | 0.81 | LIPE (0.54) | LIPETAAR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL188010 | 0.81 | ALDH1A1 (0.55) | LIPETAAR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28962614 | 0.78 | LIPE (0.51) | LIPETAAR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1444893 | 0.77 | RAD51 (0.56) | MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL7063178 | 0.77 | ELANE (0.50) | LIPETAAR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL56865 | 0.77 | KMT2A (0.50) | LIPETAAR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6912550 | 0.76 | LIPE (0.54) | LIPETAAR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30407567 | 0.76 | FAAH (0.50) | MEN1KMT2A | |
| SCHEMBL30409264 | 0.76 | FAAH (0.50) | MEN1KMT2A | |
| SCHEMBL29185989 | 0.76 | ELANE (0.51) | LIPETAAR1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616563-A | ANTITUMOR AGENTS | UNIVERSITY OF MARYLAND BALTIMORE CAMPUS (US) | 1997-04-01 | — | — | US | disclosed |
| WO-1996000061-A1 | GLUTATHIONE N-HYDROXYCARBAMOYL THIOESTERS AND METHOD OF INHIBITING NEOPLASTIC GROWTH | UNIVERSITY OF MARYLAND BALTIMORE COUNTY (US) | 1996-01-04 | — | — | WO | disclosed |