Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | MMP12 | P39900 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28592782 | 0.87 | HCAR2 (0.51) | MMP2MMP9MMP12IDO1MAOB | |
| SCHEMBL1592402 | 0.85 | MMP2 (0.51) | MMP2MMP9MMP12IDO1MAOB | |
| SCHEMBL27770677 | 0.83 | HCAR2 (0.48) | MMP2MMP9MMP12IDO1MAOB | |
| SCHEMBL3763603 | 0.82 | IDO1 (0.58) | MMP2MMP9MMP12IDO1MAOB | |
| SCHEMBL6903259 | 0.81 | ALDH1A1 (0.63) | MMP2MMP9MMP12IDO1MAOB | |
| SCHEMBL219575 | 0.80 | HCAR2 (0.65) | POLBHCAR2KMT2ALMNA | |
| M-Xylene SCHEMBL9686508 | 0.79 | ALDH1A1 (0.61) | MMP2MMP9MMP12IDO1MAOB | |
| SCHEMBL2535662 | 0.79 | HSP90AA1 (0.59) | MMP2MMP9MMP12IDO1MAOB | |
| SCHEMBL7656159 | 0.79 | IDO1 (0.59) | MMP2MMP9MMP12IDO1MAOB | |
| SCHEMBL11237868 | 0.79 | ALDH1A1 (0.61) | MMP2MMP9MMP12IDO1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670563-A | ORGANOTIN COMPOUND, PHOSPHORUS COMPOUND | CIBA-SPECIALTY CHEMICALS CORPORATION (US) | 1997-09-23 | — | — | US | disclosed |