Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 11/20 | 0.59 |
| ▸ | HTR1B | P28222 | 11/20 | 0.59 |
| ▸ | HTR2A | P28223 | 3/20 | 0.57 |
| ▸ | MPO | P05164 | 3/20 | 0.56 |
| ▸ | BRD4 | O60885 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8903222 | 0.98 | HTR1D (0.62) | HTR1DHTR1BHTR2AMPOBRD4 | |
| SCHEMBL8894091 | 0.78 | SLC6A4 (0.49) | HTR1DHTR1BBRD4 | |
| SCHEMBL8894945 | 0.78 | SLC6A4 (0.60) | HTR1DHTR1BBRD4 | |
| SCHEMBL26508375 | 0.75 | MPO (0.67) | HTR1DHTR1BHTR2AMPOBRD4 | |
| SCHEMBL26508379 | 0.75 | HTR1A (0.75) | HTR1DHTR1BHTR2AMPO | |
| SCHEMBL26508359 | 0.75 | HTR7 (0.71) | HTR1DHTR1BHTR2AMPO | |
| SCHEMBL26508389 | 0.75 | MPO (0.67) | HTR1DHTR1BHTR2AMPO | |
| SCHEMBL26508293 | 0.75 | HTR2A (0.70) | HTR1DHTR1BHTR2AMPOBRD4 | |
| SCHEMBL26508398 | 0.75 | MPO (0.94) | HTR1DHTR1BHTR2AMPO | |
| SCHEMBL26508337 | 0.75 | MPO (0.67) | HTR1DHTR1BHTR2AMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997043281-A1 | THIOPHENE- AND FURAN-TRYPTAMINE DERIVATIVES | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1997-11-20 | — | — | WO | claimed |
| WO-1997043281-A1 | THIOPHENE- AND FURAN-TRYPTAMINE DERIVATIVES | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1997-11-20 | — | — | WO | disclosed |