Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.41 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8894945 | 0.92 | SLC6A4 (0.60) | SLC6A4TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8894085 | 0.78 | HTR1D (0.59) | HTR1DHTR1BBRD4 | |
| SCHEMBL8903222 | 0.78 | HTR1D (0.62) | HTR1DHTR1BBRD4 | |
| SCHEMBL8894103 | 0.73 | TUBB4A (0.43) | SLC6A4TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8686768 | 0.70 | HTR1D (0.64) | SLC6A4HTR6HTR1DHTR1B | |
| SCHEMBL8903373 | 0.70 | HTR1D (0.62) | SLC6A4HTR6HTR1AHTR1DHTR1B | |
| SCHEMBL6971173 | 0.68 | SLC6A4 (0.60) | SLC6A4HTR6HTR1DHTR1B | |
| SCHEMBL8903215 | 0.68 | TUBB4A (0.41) | SLC6A4TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6968677 | 0.68 | SLC6A4 (0.70) | SLC6A4HTR6HTR1AHTR2CHTR1D | |
| SCHEMBL8506913 | 0.68 | SLC6A4 (0.70) | SLC6A4HTR6HTR1AHTR2CHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997043281-A1 | THIOPHENE- AND FURAN-TRYPTAMINE DERIVATIVES | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1997-11-20 | — | — | WO | claimed |
| WO-1997043281-A1 | THIOPHENE- AND FURAN-TRYPTAMINE DERIVATIVES | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1997-11-20 | — | — | WO | disclosed |