Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 5/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.37 |
| ▸ | PPOX | P50336 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8895253 | 0.83 | PPOX (0.42) | CD274DHODHBRPF1PPOXTSHR | |
| SCHEMBL9836594 | 0.73 | RORC (0.47) | DHODHPPOXRORCGAAMAPK1 | |
| SCHEMBL10576407 | 0.72 | RORC (0.46) | DHODHPPOXRORCGAAMAPK1 | |
| SCHEMBL9769699 | 0.69 | PPOX (0.46) | DHODHPPOXGAAMAPK1P2RX3 | |
| SCHEMBL10576902 | 0.69 | P2RX3 (0.46) | DHODHPPOXRORCGAAMAPK1 | |
| SCHEMBL10419791 | 0.68 | DHODH (0.48) | DHODHRORCGAAMAPK1LMNA | |
| SCHEMBL9398310 | 0.67 | PPOX (0.36) | DHODHPPOXRORCGAAMAPK1 | |
| SCHEMBL10696807 | 0.67 | RORC (0.43) | DHODHPPOXRORCGAAMAPK1 | |
| SCHEMBL27368859 | 0.67 | RORC (0.40) | DHODHPPOXRORCGAAMAPK1 | |
| SCHEMBL9769759 | 0.67 | TSHR (0.40) | DHODHPPOXGAAMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643855-A | Herbicidal imidazolones | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-07-01 | — | — | US | disclosed |
| WO-1994014817-A1 | HERBICIDAL IMIDAZOLONES AND A PROCESS FOR THEIR MANUFACTURE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-07-07 | — | — | WO | disclosed |