Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPOX | P50336 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 2/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 3/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.37 |
| ▸ | ULK1 | O75385 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8894419 | 0.83 | CD274 (0.44) | PPOXTSHRDHODHCD274BRPF1 | |
| SCHEMBL31122567 | 0.77 | ROCK2 (0.52) | ROCK2SRCFLT3HTR2AHTR2C | |
| SCHEMBL9769699 | 0.76 | PPOX (0.46) | PPOXTSHRDHODHL3MBTL1 | |
| SCHEMBL9836594 | 0.75 | RORC (0.47) | PPOXDHODH | |
| SCHEMBL9769759 | 0.74 | TSHR (0.40) | PPOXTSHRDHODHL3MBTL1 | |
| SCHEMBL10576407 | 0.74 | RORC (0.46) | PPOXDHODH | |
| SCHEMBL9619955 | 0.74 | PPOX (0.42) | PPOXTSHRDHODHL3MBTL1 | |
| SCHEMBL31122588 | 0.71 | KMT2A (0.64) | ROCK2SRCHTR2CHDAC2L3MBTL1 | |
| SCHEMBL9397328 | 0.71 | L3MBTL1 (0.53) | TSHRL3MBTL1 | |
| SCHEMBL10882564 | 0.70 | MAPT (0.38) | PPOXDHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643855-A | Herbicidal imidazolones | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-07-01 | — | — | US | disclosed |
| WO-1994014817-A1 | HERBICIDAL IMIDAZOLONES AND A PROCESS FOR THEIR MANUFACTURE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-07-07 | — | — | WO | disclosed |