Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PPOX | P50336 | 3/20 | 0.39 |
| ▸ | DHODH | Q02127 | 4/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9769699 | 0.89 | PPOX (0.46) | TSHRPPOXDHODHGLAHTT | |
| SCHEMBL8895253 | 0.74 | PPOX (0.42) | TSHRPPOXDHODHL3MBTL1 | |
| SCHEMBL9769706 | 0.74 | PPOX (0.43) | TSHRPPOXGLAHTTTAS1R3 | |
| SCHEMBL9619955 | 0.73 | PPOX (0.42) | TSHRPPOXDHODHTAS1R3TAS1R1 | |
| SCHEMBL9769666 | 0.72 | RAB9A (0.44) | TSHRGLAHTTTAS1R3TAS1R1 | |
| SCHEMBL9836594 | 0.71 | RORC (0.47) | PPOXDHODHNPSR1LMNATP53 | |
| SCHEMBL10576902 | 0.70 | P2RX3 (0.46) | TSHRPPOXDHODHNPSR1LMNA | |
| SCHEMBL10940940 | 0.70 | PPOX (0.44) | TSHRPPOXDHODHALDH1A1MAPK1 | |
| SCHEMBL10576407 | 0.70 | RORC (0.46) | PPOXDHODHGLANPSR1LMNA | |
| SCHEMBL10619915 | 0.69 | DHODH (0.37) | TSHRPPOXDHODHNPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2083359-A | — | — | None | — | — | JP | disclosed |
| US-5068365-A | Herbicides | TOSOH CORPORATION (JP) | 1991-11-26 | — | — | US | disclosed |
| JP-H0283359-A | HEXAHYDROPHTHALIC ACID ANILIDE DERIVATIVE, ITS PRODUCTION AND HERBICIDE CONTAINING THE SAME DERIVATIVE AS ACTIVE COMPONENT | TOSOH CORP | 1990-03-23 | — | — | JP | disclosed |
| EP-0326764-A2 | Hexahydrophthalic anilide derivatives and herbicide compositions containing the same | Tosoh Corporation (JP) | 1989-08-09 | — | — | EP | disclosed |