Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.91 |
| ▸ | TSHR | P16473 | 2/20 | 0.91 |
| ▸ | GLA | P06280 | 1/20 | 0.91 |
| ▸ | HPGD | P15428 | 1/20 | 0.91 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.91 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.91 |
| ▸ | BLM | P54132 | 1/20 | 0.91 |
| ▸ | CA1 | P00915 | 15/20 | 0.59 |
| ▸ | CA2 | P00918 | 15/20 | 0.59 |
| ▸ | CA9 | Q16790 | 13/20 | 0.59 |
| ▸ | CA12 | O43570 | 4/20 | 0.59 |
| ▸ | CA7 | P43166 | 4/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.59 |
| ▸ | CA3 | P07451 | 3/20 | 0.59 |
| ▸ | CA4 | P22748 | 3/20 | 0.59 |
| ▸ | CA6 | P23280 | 3/20 | 0.59 |
| ▸ | CA5A | P35218 | 3/20 | 0.59 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL3196243 | 1.00 | RECQL (0.91) | RECQLTSHRGLAHPGDMAPK1 | |
| Potassium Ion SCHEMBL1268318 | 1.00 | RECQL (0.91) | RECQLTSHRGLAHPGDMAPK1 | |
| Potassium Ion SCHEMBL6130040 | 1.00 | RECQL (0.91) | RECQLTSHRGLAHPGDMAPK1 | |
| Potassium Ion SCHEMBL10600170 | 1.00 | RECQL (0.91) | RECQLTSHRGLAHPGDMAPK1 | |
| Potassium Ion SCHEMBL379323 | 1.00 | RECQL (0.91) | RECQLTSHRGLAHPGDMAPK1 | |
| Potassium Ion SCHEMBL1269089 | 1.00 | RECQL (0.91) | RECQLTSHRGLAHPGDMAPK1 | |
| Potassium Ion SCHEMBL10599158 | 1.00 | RECQL (0.91) | RECQLTSHRGLAHPGDMAPK1 | |
| Potassium Ion SCHEMBL5694816 | 1.00 | RECQL (0.91) | RECQLTSHRGLAHPGDMAPK1 | |
| Potassium Ion SCHEMBL10599511 | 1.00 | RECQL (0.91) | RECQLTSHRGLAHPGDMAPK1 | |
| Potassium Ion SCHEMBL29701335 | 1.00 | RECQL (0.91) | RECQLTSHRGLAHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0207516-A1 | An ingestible product containing a sweetness inhibitor and process for inhibiting sweetness in an ingestible product | GENERAL FOODS CORPORATION (US) | 1987-01-07 | — | — | EP | claimed |
| US-5599715-A | SOLUTION CONTAINING BUFFER(S) AND SULFATE SURFACTANT; NONCRYSTALLIZING AT LOW TEMPERATURE; IMMUNOASSAYS | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1997-02-04 | — | — | US | disclosed |
| EP-0456308-A1 | Immunoreagent composition, test kit and rapid assay for human chorionic gonadotropin | CLINICAL DIAGNOSTIC SYSTEMS, INC. (US) | 1991-11-13 | — | — | EP | disclosed |
| US-4965191-A | MEASURING HUMAN CHORIONIC GONADOTROPIN AS PREGNANCY TEST; COMPLEXING LIGAND AND DETECTABLE LABELED RECEPTORS | EASTMAN KODAK COMPANY (US) | 1990-10-23 | — | — | US | disclosed |
| EP-0328413-A2 | Sodium decyl sulfate wash solution, test kit and method for the determination of an immunological ligand | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-08-16 | — | — | EP | disclosed |
| US-4857402-A | Magnetic recording medium | FUJI PHOTO FILM CO., LTD. (JP) | 1989-08-15 | — | — | US | disclosed |
| EP-0207516-A1 | An ingestible product containing a sweetness inhibitor and process for inhibiting sweetness in an ingestible product | GENERAL FOODS CORPORATION (US) | 1987-01-07 | — | — | EP | disclosed |