Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8902250 | 0.84 | ACHE (0.34) | SIGMAR1TMEM97 | |
| SCHEMBL7315444 | 0.56 | TSHR (0.59) | ALDH1A1KDM4ETSHRMAPTDRD4 | |
| SCHEMBL11856358 | 0.54 | KDM4E (0.70) | SIGMAR1ALDH1A1KDM4ETSHRSMN1; SMN2 | |
| SCHEMBL8636775 | 0.54 | CNR1 (0.55) | SIGMAR1ALDH1A1KDM4ECYP3A4CYP2C19 | |
| SCHEMBL272484 | 0.53 | KDM4E (0.47) | ALDH1A1KDM4ETSHRLMNAMAPT | |
| SCHEMBL6502154 | 0.53 | ALDH1A1 (0.51) | SIGMAR1KMT2AALDH1A1KDM4ETSHR | |
| SCHEMBL235080 | 0.52 | KDM4E (0.65) | SIGMAR1ALDH1A1KDM4ETSHRSMN1; SMN2 | |
| SCHEMBL28854385 | 0.52 | SIGMAR1 (0.43) | SIGMAR1KMT2AKDM4ECYP3A4CYP2C19 | |
| SCHEMBL10335650 | 0.52 | SMN1; SMN2 (0.46) | SIGMAR1ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL5088833 | 0.51 | KDM4E (0.46) | SIGMAR1KMT2AALDH1A1KDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997043282-A2 | BENZOTHIAZOLINONES AS ANTI-ASTHMATIC AGENTS | KLINGE PHARMA GMBH (DE) | 1997-11-20 | — | — | WO | disclosed |