Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8894966 | 0.84 | SIGMAR1 (0.35) | SIGMAR1TMEM97 | |
| SCHEMBL8903406 | 0.82 | ACHE (0.32) | ACHEP2RX7 | |
| SCHEMBL8902245 | 0.61 | TMEM97 (0.47) | ACHESIGMAR1TMEM97 | |
| SCHEMBL8902235 | 0.60 | NPY5R (0.56) | SIGMAR1TMEM97 | |
| SCHEMBL6762041 | 0.60 | ALOX15 (0.44) | ACHEGRIN2BP2RX7 | |
| SCHEMBL9434876 | 0.59 | ALOX15 (0.50) | — | |
| SCHEMBL27699518 | 0.59 | — | — | |
| SCHEMBL30168198 | 0.58 | TRPV4 (0.44) | — | |
| SCHEMBL9570335 | 0.57 | SIGMAR1 (0.71) | ACHEGRIN2BSIGMAR1TMEM97 | |
| Hydrochloric Acid SCHEMBL8869860 | 0.56 | SIGMAR1 (0.69) | ACHESIGMAR1TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997043282-A2 | BENZOTHIAZOLINONES AS ANTI-ASTHMATIC AGENTS | KLINGE PHARMA GMBH (DE) | 1997-11-20 | — | — | WO | disclosed |