Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 3/20 | 0.64 |
| ▸ | TK1 | P04183 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.60 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.60 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.60 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | TK2 | O00142 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Deoxyuridine SCHEMBL9219261 | 1.00 | DUT (0.64) | DUTTK1LMNASMN1; SMN2SLC28A1 | |
| Deoxyuridine SCHEMBL2641582 | 1.00 | DUT (0.64) | DUTTK1LMNASMN1; SMN2SLC28A1 | |
| Deoxyuridine SCHEMBL114598 | 1.00 | DUT (0.64) | DUTTK1LMNASMN1; SMN2SLC28A1 | |
| Deoxyuridine SCHEMBL19841232 | 1.00 | DUT (0.64) | DUTTK1LMNASMN1; SMN2SLC28A1 | |
| Deoxyuridine SCHEMBL9708874 | 1.00 | DUT (0.64) | DUTTK1LMNASMN1; SMN2SLC28A1 | |
| Deoxyuridine SCHEMBL24512520 | 1.00 | DUT (0.64) | DUTTK1LMNASMN1; SMN2SLC28A1 | |
| Deoxyuridine SCHEMBL4847464 | 1.00 | DUT (0.64) | DUTTK1LMNASMN1; SMN2SLC28A1 | |
| Deoxyuridine SCHEMBL391224 | 1.00 | DUT (0.64) | DUTTK1LMNASMN1; SMN2SLC28A1 | |
| Deoxyuridine SCHEMBL9219265 | 1.00 | DUT (0.64) | DUTTK1LMNASMN1; SMN2SLC28A1 | |
| Deoxyuridine SCHEMBL28844 | 1.00 | DUT (0.64) | DUTTK1LMNASMN1; SMN2SLC28A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6605713-B1 | Contacting D-nucleic acids with a racemic mixture of the target molecule and allow for binding; producing L-nucleic acids; in vitro selection of DNA/RNA with high binding affinity and stability | FURSTE JENS PETER (DE) | 2003-08-12 | — | — | US | claimed |
| EP-1292313-A2 | METHODS FOR TREATING HEPATITIS DELTA VIRUS INFECTION WITH BETA-L-2' DEOXY-NUCLEOSIDES | Idenix (Cayman) Limited (KY) | 2003-03-19 | — | — | EP | claimed |
| WO-2001091737-A2 | METHODS FOR TREATING HEPATITIS DELTA VIRUS INFECTION WITH BETA-L-2' DEOXY-NUCLEOSIDES | IDENIX (CAYMAN) LIMITED (KY) | 2001-12-06 | — | — | WO | claimed |
| US-20240026358-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-01-25 | — | — | US | disclosed |
| US-20240026358-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-01-25 | — | — | US | disclosed |
| US-20230010671-A1 | PROTON ACTIVATED ATOMIC MEDICINE | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2023-01-12 | — | — | US | disclosed |
| WO-2022099159-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2022-05-12 | — | — | WO | disclosed |
| US-20210214730-A1 | CYTOTOXIC FLUOROPYRIMIDINE POLYMERS AND METHODS OF USE THEREOF | WAKE FOREST UNIVERSITY HEALTH SCIENCES | 2021-07-15 | — | — | US | disclosed |
| US-20210196723-A1 | Modulators of DUX4 for Regulation of Muscle Function | SONIC MASTER LTD (VG) | 2021-07-01 | — | — | US | disclosed |
| US-10933068-B2 | Modulators of DUX4 for regulation of muscle function | SONIC MASTER LIMITED (VG) | 2021-03-02 | — | — | US | disclosed |
| US-20210024564-A1 | PROTON ACTIVATED ATOMIC MEDICINE | UNIVERSITY OF VIRGINIA | 2021-01-28 | — | — | US | disclosed |
| EP-0717628-A1 | NUCLEOSIDES WITH ANTI-HEPATITIS B VIRUS ACTIVITY | EMORY UNIVERSITY (US) | 1996-06-26 | — | — | EP | disclosed |
| EP-0707481-A4 | — | — | 1996-05-29 | — | — | EP | disclosed |
| WO-1996014073-A1 | TREATMENT OF UROGENITAL CANCER WITH BORON NEUTRON CAPTURE THERAPY | EMORY UNIVERSITY (US) | 1996-05-17 | — | — | WO | disclosed |
| EP-0707481-A1 | L-2',3'-DIDEOXY NUCLEOSIDE ANALOGS AS ANTI-HEPATITIS B (HBV) AND ANTI-HIV AGENTS | YALE UNIVERSITY (US) | 1996-04-24 | — | — | EP | disclosed |
| EP-0691981-A1 | TUMOR TARGETING WITH L-ENANTIOMERIC OLIGONUCLEOTIDE CONJUGATES OF IMMUNOREAGENTS AND OF CHELATED RADIONUCLIDES | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-01-17 | — | — | EP | disclosed |
| WO-1995015333-A1 | NUCLEOSIDES AND OLIGONUCLEOTIDES CONTAINING BORON CLUSTERS | EMORY UNIVERSITY (US) | 1995-06-08 | — | — | WO | disclosed |
| WO-1995007086-A1 | NUCLEOSIDES WITH ANTI-HEPATITIS B VIRUS ACTIVITY | EMORY UNIVERSITY (US) | 1995-03-16 | — | — | WO | disclosed |
| WO-1994027616-A1 | L-2',3'-DIDEOXY NUCLEOSIDE ANALOGS AS ANTI-HEPATITIS B (HBV) AND ANTI-HIV AGENTS | YALE UNIVERSITY (US) | 1994-12-08 | — | — | WO | disclosed |
| WO-1994020523-A1 | TUMOR TARGETING WITH L-ENANTIOMERIC OLIGONUCLEOTIDE CONJUGATES OF IMMUNOREAGENTS AND OF CHELATED RADIONUCLIDES | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-09-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210196723-A1 | Modulators of DUX4 for Regulation of Muscle Function | DDX21, MBNL1, MECP2 | DUT 568/4885TK1 2815/4885LMNA 1943/4885 |
| US-10933068-B2 | Modulators of DUX4 for regulation of muscle function | DDX21, MBNL1, MECP2 | DUT 556/4885TK1 2927/4885LMNA 2031/4885 |
| US-20210024564-A1 | PROTON ACTIVATED ATOMIC MEDICINE | NUDT1, TK1, TK2 | DUT 7/4885TK1 2/4885LMNA 1722/4885 |
| US-20230010671-A1 | PROTON ACTIVATED ATOMIC MEDICINE | NUDT1, TK1, TK2 | DUT 7/4885TK1 2/4885LMNA 1722/4885 |
| US-20210214730-A1 | CYTOTOXIC FLUOROPYRIMIDINE POLYMERS AND METHODS OF USE THEREOF | DCTD, CDA, DPYD | DUT 6/4885TK1 198/4885LMNA 1823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.