Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.78 |
| ▸ | MEN1 | O00255 | 1/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.78 |
| ▸ | RPLP1 | P05386 | 1/20 | 0.65 |
| ▸ | RPLP0 | P05388 | 1/20 | 0.65 |
| ▸ | RPS17 | P08708 | 1/20 | 0.65 |
| ▸ | RPSA | P08865 | 1/20 | 0.65 |
| ▸ | RPS2 | P15880 | 1/20 | 0.65 |
| ▸ | RPL35A | P18077 | 1/20 | 0.65 |
| ▸ | RPL7 | P18124 | 1/20 | 0.65 |
| ▸ | RPL17 | P18621 | 1/20 | 0.65 |
| ▸ | RPS4Y1 | P22090 | 1/20 | 0.65 |
| ▸ | RPS3 | P23396 | 1/20 | 0.65 |
| ▸ | RPS12 | P25398 | 1/20 | 0.65 |
| ▸ | RPL13 | P26373 | 1/20 | 0.65 |
| ▸ | RPL10 | P27635 | 1/20 | 0.65 |
| ▸ | RPL12 | P30050 | 1/20 | 0.65 |
| ▸ | RPL9; RPL9P7; RPL9P8; RPL9P9 | P32969 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiamphenicol SCHEMBL34635 | 1.00 | LMNA (1.00) | LMNATSHRCYP3A4MEN1KMT2A | |
| Racephenicol SCHEMBL30277834 | 1.00 | LMNA (1.00) | LMNATSHRCYP3A4MEN1KMT2A | |
| Thiamphenicol SCHEMBL6245287 | 0.99 | LMNA (0.97) | LMNATSHRCYP3A4MEN1KMT2A | |
| Florfenicol SCHEMBL3834996 | 0.94 | LMNA (0.90) | LMNATSHRCYP3A4MEN1KMT2A | |
| Thiamphenicol SCHEMBL10380783 | 0.94 | LMNA (0.88) | LMNATSHRCYP3A4MEN1KMT2A | |
| Thiamphenicol SCHEMBL401137 | 0.93 | LMNA (0.86) | LMNATSHRCYP3A4MEN1KMT2A | |
| Racephenicol SCHEMBL30388685 | 0.92 | LMNA (0.84) | LMNATSHRCYP3A4MEN1KMT2A | |
| Thiamphenicol SCHEMBL365612 | 0.92 | LMNA (0.84) | LMNATSHRCYP3A4MEN1KMT2A | |
| Thiamphenicol SCHEMBL9295760 | 0.91 | RPLP1 (0.83) | LMNATSHRCYP3A4MEN1KMT2A | |
| Florfenicol SCHEMBL3637832 | 0.88 | LMNA (1.00) | LMNATSHRCYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507153-B1 | Stereoisomeric enrichment of 2-amino-3-hydroxy-3-phenyl-propionic acids | CELGENE CORP (US) | 1997-07-09 | — | — | EP | claimed |
| US-5346828-A | Stereoisomeric enrichment of 2-amino-3-hydroxy-3-phenylpropionic acids using d-threonine aldolase | CELGENE CORPORATION (US) | 1994-09-13 | — | — | US | claimed |
| EP-0507153-A2 | Stereoisomeric enrichment of 2-amino-3-hydroxy-3-phenyl-propionic acids | CELGENE CORPORATION (US) | 1992-10-07 | — | — | EP | claimed |
| CN-119738497-A | Method for detecting thiamphenicol or related substances of thiamphenicol preparation | 北京四环科宝制药股份有限公司 | 2025-04-01 | — | — | CN | disclosed |
| EP-3607084-B1 | A METHOD FOR TESTING ANTIMICROBIAL SUSCEPTIBILITY | UNIV WESTERN AUSTRALIA (AU) | 2024-05-01 | — | — | EP | disclosed |
| CN-117686628-A | Method for detecting thiamphenicol genotoxic impurities | 江苏恒盛药业有限公司 | 2024-03-12 | — | — | CN | disclosed |
| US-20210292807-A1 | METHOD FOR TESTING ANTIMICROBIAL SUSCEPTIBILITY | THE UNIVERSITY OF WESTERN AUSTRALIA (AU) | 2021-09-23 | — | — | US | disclosed |
| CN-109928901-B | Synthetic method of florfenicol intermediate | 上海医药工业研究院 | 2020-12-11 | — | — | CN | disclosed |
| EP-3718534-A1 | PHARMACEUTICAL COMPOSITION CONTAINING ETHANOL AND AN ANTIBIOTIC, AND SUITABLE FOR FORMING A SOLID MASS IN CONTACT WITH A SALINE SOLUTION - ASSOCIATED PRODUCT AND DEVICE FOR CONCENTRATION AND LOCAL DELIVERY | Gelnesis (FR) | 2020-10-07 | — | — | EP | disclosed |
| WO-2017133517-A1 | PHOSPHAMIDE DERIVATIVE, METHOD FOR MANUFACTURING THE SAME, AND USES THEREOF | 四川海思科制药有限公司 | 2017-08-10 | — | — | WO | disclosed |
| EP-0507153-B1 | Stereoisomeric enrichment of 2-amino-3-hydroxy-3-phenyl-propionic acids | CELGENE CORP (US) | 1997-07-09 | — | — | EP | disclosed |
| US-5346828-A | Stereoisomeric enrichment of 2-amino-3-hydroxy-3-phenylpropionic acids using d-threonine aldolase | CELGENE CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| EP-0507153-A2 | Stereoisomeric enrichment of 2-amino-3-hydroxy-3-phenyl-propionic acids | CELGENE CORPORATION (US) | 1992-10-07 | — | — | EP | disclosed |
| US-4945181-A | Method for resolution of racemic thiamphenicol precursors and intermediates therefor | BOEHRINGER MANNHEIM GMBH (DE) | 1990-07-31 | — | — | US | disclosed |