SCHEMBL8895693

SCHEMBL8895693

CCc1ccccc1Nc1ccc(-c2ccc(Nc3ccccc3CC)cc2-c2ccccc2)c(-c2ccccc2)c1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.43
ALDH1A1 P00352 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
GAA P10253 2/20 0.43
MAPT P10636 2/20 0.43
KDM4E B2RXH2 1/20 0.43
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
KCNK3 O14649 1/20 0.40
KCNK9 Q9NPC2 1/20 0.40
HTT P42858 1/20 0.39
APP P05067 1/20 0.39
CLCN2 P51788 1/20 0.38
PTGS2 P35354 1/20 0.38
P2RY2 P41231 1/20 0.37
P2RY4 P51582 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8418765 0.88 SMN1; SMN2 (0.36) RAB9AALDH1A1SMN1; SMN2GAAMAPT
SCHEMBL8417375 0.85 SOAT1 (0.37) APP
SCHEMBL9423214 0.81 ADRA2B (0.36) ALDH1A1SMN1; SMN2MAPTMEN1KMT2A
SCHEMBL14320839 0.79 HTT (0.50) RAB9AALDH1A1SMN1; SMN2GAAMAPT
SCHEMBL9006076 0.79 MAPK14 (0.44) RAB9AALDH1A1SMN1; SMN2GAAMAPT
SCHEMBL8895701 0.79 RAB9A (0.41) RAB9AALDH1A1SMN1; SMN2GAAMAPT
SCHEMBL3148744 0.78 MEN1 (0.48) RAB9AALDH1A1SMN1; SMN2GAAMAPT
SCHEMBL6029657 0.77 MAPT (0.50) RAB9AALDH1A1SMN1; SMN2GAAMAPT
SCHEMBL29657744 0.77 MAPT (0.50) RAB9AALDH1A1SMN1; SMN2GAAMAPT
SCHEMBL8418919 0.77 TSHR (0.39) ALDH1A1SMN1; SMN2MAPTKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0582722-B1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR MADE FROM POLYCARBONATE POLYMER IDEMITSU KOSAN CO (JP) 1997-11-12 EP disclosed
EP-0411192-B1 Electrophotographic photoreceptor IDEMITSU KOSAN CO (JP) 1995-06-07 EP disclosed
EP-0597128-A1 ESTER POLYMER, PRODUCTION THEREOF, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR MADE THEREFROM IDEMITSU KOSAN COMPANY LIMITED (JP) 1994-05-18 EP disclosed
EP-0582722-A1 POLYCARBONATE POLYMER, PRODUCTION THEREOF, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR MADE THEREFROM IDEMITSU KOSAN COMPANY LIMITED (JP) 1994-02-16 EP disclosed
EP-0411192-A1 Electrophotographic photoreceptor IDEMITSU KOSAN COMPANY LIMITED (JP) 1991-02-06 EP disclosed