SCHEMBL8895701

SCHEMBL8895701

CCc1ccccc1Nc1ccc(-c2ccc(Nc3ccccc3CC)c(-c3ccccc3)c2-c2ccccc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
FABP4 P15090 4/20 0.39
P2RY2 P41231 1/20 0.36
P2RY4 P51582 1/20 0.36
FABP3 P05413 2/20 0.36
FABP5 Q01469 1/20 0.36
HTT P42858 1/20 0.35
POLB P06746 1/20 0.35
PTGS1 P23219 1/20 0.35
MAPKAPK2 P49137 1/20 0.35
NPC1 O15118 1/20 0.35
MAPK13 O15264 1/20 0.34
MAPK12 P53778 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8418766 0.90 FABP4 (0.38) RAB9AKDM4EALDH1A1GAAMAPT
SCHEMBL8417377 0.87 SOAT1 (0.34) RAB9AKDM4EALDH1A1GAAMAPT
SCHEMBL1727994 0.83 AKR1B1 (0.33) RAB9AMAPTSMN1; SMN2MEN1KMT2A
SCHEMBL6131762 0.82 FABP4 (0.43) RAB9AKDM4EALDH1A1GAAMAPT
SCHEMBL8418920 0.80 HTT (0.35) RAB9AKDM4EALDH1A1MAPTSMN1; SMN2
SCHEMBL31265542 0.79 ALDH1A1 (0.45) KDM4EALDH1A1GAAMAPTSMN1; SMN2
SCHEMBL3475626 0.79 FABP4 (0.45) RAB9AKDM4EALDH1A1GAAMAPT
SCHEMBL3148744 0.79 MEN1 (0.48) RAB9AKDM4EALDH1A1GAAMAPT
SCHEMBL6131761 0.79 HPGD (0.52) RAB9AKDM4EGAAMAPTSMN1; SMN2
SCHEMBL8895693 0.79 RAB9A (0.43) RAB9AKDM4EALDH1A1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0582722-B1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR MADE FROM POLYCARBONATE POLYMER IDEMITSU KOSAN CO (JP) 1997-11-12 EP disclosed
EP-0411192-B1 Electrophotographic photoreceptor IDEMITSU KOSAN CO (JP) 1995-06-07 EP disclosed
EP-0597128-A1 ESTER POLYMER, PRODUCTION THEREOF, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR MADE THEREFROM IDEMITSU KOSAN COMPANY LIMITED (JP) 1994-05-18 EP disclosed
EP-0582722-A1 POLYCARBONATE POLYMER, PRODUCTION THEREOF, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR MADE THEREFROM IDEMITSU KOSAN COMPANY LIMITED (JP) 1994-02-16 EP disclosed
EP-0411192-A1 Electrophotographic photoreceptor IDEMITSU KOSAN COMPANY LIMITED (JP) 1991-02-06 EP disclosed