Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 5/20 | 0.56 |
| ▸ | CTSL | P07711 | 2/20 | 0.56 |
| ▸ | CTSS | P25774 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 2/20 | 0.50 |
| ▸ | CTSK | P43235 | 7/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8898663 | 0.88 | HSP90AA1 (0.54) | CTSBCTSLCTSSMEN1KMT2A | |
| SCHEMBL8898176 | 0.86 | MEN1 (0.49) | CTSBCTSLCTSSMEN1KMT2A | |
| SCHEMBL8895307 | 0.86 | CTSK (0.57) | CTSBCTSLCTSSMEN1KMT2A | |
| SCHEMBL8896567 | 0.86 | CTSK (0.57) | CTSBCTSLCTSSMEN1KMT2A | |
| SCHEMBL8895811 | 0.84 | CTSL (0.46) | CTSBCTSLCTSSMEN1KMT2A | |
| SCHEMBL8614503 | 0.80 | FOLH1 (0.50) | CTSBCTSLCTSSMEN1KMT2A | |
| SCHEMBL15926429 | 0.79 | CTSB (0.65) | CTSBCTSLCTSSMEN1KMT2A | |
| SCHEMBL14148468 | 0.79 | CTSB (0.65) | CTSBCTSLCTSSMEN1KMT2A | |
| SCHEMBL25571941 | 0.78 | MEN1 (0.65) | CTSBCTSLCTSSMEN1KMT2A | |
| SCHEMBL8897466 | 0.78 | CTSK (0.54) | CTSBCTSLCTSSMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5656604-A | HYPOTENSIVE AGENT; ENDOTHELIN ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-12 | — | — | US | disclosed |