Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.54 |
| ▸ | CTSB | P07858 | 4/20 | 0.54 |
| ▸ | CTSL | P07711 | 3/20 | 0.54 |
| ▸ | CTSS | P25774 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8895307 | 0.90 | CTSK (0.57) | CTSKCTSBCTSLCTSSMEN1 | |
| SCHEMBL8896567 | 0.90 | CTSK (0.57) | CTSKCTSBCTSLCTSSMEN1 | |
| SCHEMBL8896176 | 0.88 | CTSK (0.59) | CTSKCTSBCTSLCTSS | |
| SCHEMBL8614433 | 0.87 | CTSK (0.48) | CTSKCTSBCTSLCTSSMEN1 | |
| SCHEMBL15130921 | 0.84 | CTSL (0.72) | CTSKCTSBCTSLCTSSMEN1 | |
| SCHEMBL8612045 | 0.79 | FOLH1 (0.52) | CTSKCTSBCTSLCTSSMEN1 | |
| SCHEMBL8612042 | 0.79 | FOLH1 (0.52) | CTSKCTSBCTSLCTSSMEN1 | |
| SCHEMBL8898663 | 0.79 | HSP90AA1 (0.54) | CTSKCTSBCTSLCTSSMEN1 | |
| SCHEMBL16867535 | 0.79 | CTSK (0.49) | CTSKCTSBMEN1KMT2A | |
| SCHEMBL8895941 | 0.78 | CTSB (0.56) | CTSKCTSBCTSLCTSSMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5656604-A | HYPOTENSIVE AGENT; ENDOTHELIN ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-12 | — | — | US | disclosed |