Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8895311 | 1.00 | CTSL (0.46) | CTSLCTSBCTSSCTSKMEN1 | |
| SCHEMBL8897470 | 0.91 | CTSL (0.43) | CTSLCTSBCTSSCTSKMEN1 | |
| SCHEMBL8898668 | 0.88 | CTSL (0.41) | CTSLCTSBCTSSCTSKMEN1 | |
| SCHEMBL8895944 | 0.87 | CTSL (0.45) | CTSLCTSBCTSSCTSKMEN1 | |
| SCHEMBL8896188 | 0.83 | CTSL (0.46) | CTSLCTSBCTSSCTSKANPEP | |
| SCHEMBL8896183 | 0.83 | CTSL (0.46) | CTSLCTSBCTSSCTSKANPEP | |
| SCHEMBL8895815 | 0.82 | DPP4 (0.45) | CTSLCTSBCTSSCTSKMEN1 | |
| SCHEMBL8898177 | 0.80 | ALDH1A1 (0.45) | CTSLCTSBCTSSMEN1KMT2A | |
| SCHEMBL8613294 | 0.80 | FOLH1 (0.49) | CTSLCTSBCTSSCTSKMEN1 | |
| SCHEMBL8613767 | 0.80 | FOLH1 (0.49) | CTSLCTSBCTSSCTSKMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5656604-A | HYPOTENSIVE AGENT; ENDOTHELIN ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-12 | — | — | US | disclosed |