Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.43 |
| ▸ | CTSB | P07858 | 3/20 | 0.43 |
| ▸ | CTSK | P43235 | 3/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CTSH | P09668 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8895311 | 0.91 | CTSL (0.46) | CTSLCTSBCTSKCTSSMMP9 | |
| SCHEMBL8896571 | 0.91 | CTSL (0.46) | CTSLCTSBCTSKCTSSMMP9 | |
| SCHEMBL8896188 | 0.86 | CTSL (0.46) | CTSLCTSBCTSKCTSS | |
| SCHEMBL8896183 | 0.86 | CTSL (0.46) | CTSLCTSBCTSKCTSS | |
| SCHEMBL8898668 | 0.80 | CTSL (0.41) | CTSLCTSBCTSKCTSSMEN1 | |
| SCHEMBL8895944 | 0.79 | CTSL (0.45) | CTSLCTSBCTSKCTSSMEN1 | |
| SCHEMBL8612045 | 0.78 | FOLH1 (0.52) | CTSLCTSBCTSKCTSSMMP9 | |
| SCHEMBL8612042 | 0.78 | FOLH1 (0.52) | CTSLCTSBCTSKCTSSMMP9 | |
| SCHEMBL8897466 | 0.77 | CTSK (0.54) | CTSLCTSBCTSKCTSSMMP9 | |
| SCHEMBL8897474 | 0.76 | PPARG (0.36) | MEN1KMT2ASMN1; SMN2HTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5656604-A | HYPOTENSIVE AGENT; ENDOTHELIN ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-12 | — | — | US | disclosed |