Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | CCR1 | P32246 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 3/20 | 0.40 |
| ▸ | CTSB | P07858 | 3/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | ACE | P12821 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8895944 | 0.84 | CTSL (0.45) | KMT2AMEN1CTSLCTSBCTSK | |
| SCHEMBL8898668 | 0.83 | CTSL (0.41) | KMT2AMEN1CTSLCTSBCTSK | |
| SCHEMBL8608760 | 0.82 | FOLH1 (0.44) | DPP4CCR1F2RL1ALDH1A1 | |
| SCHEMBL8898177 | 0.82 | ALDH1A1 (0.45) | KMT2AMEN1CTSLCTSBCTSS | |
| SCHEMBL8896571 | 0.82 | CTSL (0.46) | KMT2AMEN1CTSLCTSBCTSK | |
| SCHEMBL8895311 | 0.82 | CTSL (0.46) | KMT2AMEN1CTSLCTSBCTSK | |
| SCHEMBL8895811 | 0.80 | CTSL (0.46) | DPP4CCR1KMT2AMEN1CTSL | |
| SCHEMBL8896159 | 0.80 | ACE (0.45) | KMT2AMEN1ACEMMP13CYP3A4 | |
| SCHEMBL8898654 | 0.80 | ACE (0.45) | KMT2AMEN1ACEMMP13CYP3A4 | |
| SCHEMBL8895820 | 0.76 | ACE (0.41) | CTSLCTSBCTSKACEMMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5656604-A | HYPOTENSIVE AGENT; ENDOTHELIN ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-12 | — | — | US | disclosed |