Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.45 |
| ▸ | CTSB | P07858 | 2/20 | 0.45 |
| ▸ | CTSS | P25774 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 2/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8898668 | 0.88 | CTSL (0.41) | CTSLCTSBCTSSMEN1KMT2A | |
| SCHEMBL8898177 | 0.87 | ALDH1A1 (0.45) | CTSLCTSBCTSSMEN1KMT2A | |
| SCHEMBL8896571 | 0.87 | CTSL (0.46) | CTSLCTSBCTSSMEN1KMT2A | |
| SCHEMBL8895311 | 0.87 | CTSL (0.46) | CTSLCTSBCTSSMEN1KMT2A | |
| SCHEMBL8895815 | 0.84 | DPP4 (0.45) | CTSLCTSBCTSSMEN1KMT2A | |
| SCHEMBL8614503 | 0.79 | FOLH1 (0.50) | CTSLCTSBCTSSMEN1KMT2A | |
| SCHEMBL8897470 | 0.79 | CTSL (0.43) | CTSLCTSBCTSSMEN1KMT2A | |
| SCHEMBL8897280 | 0.78 | PPARG (0.45) | MEN1KMT2ASMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL8897285 | 0.78 | PPARG (0.45) | MEN1KMT2ASMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL8895941 | 0.78 | CTSB (0.56) | CTSLCTSBCTSSMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5656604-A | HYPOTENSIVE AGENT; ENDOTHELIN ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-12 | — | — | US | disclosed |