Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.50 |
| ▸ | IDH1 | O75874 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22550294 | 0.96 | CALM1 (0.55) | ALDH1A1KDM4EHTTSMN1; SMN2TSHR | |
| SCHEMBL8896665 | 0.96 | TSHR (0.55) | ALDH1A1KDM4EHTTSMN1; SMN2TSHR | |
| SCHEMBL9816693 | 0.94 | SRD5A2 (0.58) | ALDH1A1KDM4EHTTSMN1; SMN2TSHR | |
| Ethylene Glycol SCHEMBL28545403 | 0.88 | TSHR (0.51) | ALDH1A1KDM4EHTTSMN1; SMN2TSHR | |
| SCHEMBL8939741 | 0.87 | KDM4E (0.44) | ALDH1A1KDM4EHTTSMN1; SMN2TSHR | |
| SCHEMBL21549624 | 0.87 | MAOB (0.67) | ALDH1A1SMN1; SMN2MAOBMEN1KMT2A | |
| SCHEMBL27630414 | 0.87 | LTA4H (0.57) | ALDH1A1KDM4EHTTSMN1; SMN2SRD5A2 | |
| SCHEMBL11178465 | 0.83 | SRD5A2 (0.51) | ALDH1A1KDM4EHTTSMN1; SMN2TDP1 | |
| SCHEMBL10269397 | 0.82 | SRD5A2 (0.68) | TSHRSRD5A2LTA4HCALM1IDH1 | |
| SCHEMBL4025817 | 0.82 | LTA4H (0.75) | ALDH1A1KDM4ESMN1; SMN2TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11230520-B2 | Silylations of aromatic substrates with base-activated organosilanes | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2022-01-25 | — | — | US | disclosed |
| US-20210122701-A1 | SILYLATIONS OF AROMATIC SUBSTRATES WITH BASE-ACTIVATED ORGANOSILANES | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2021-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11230520-B2 | Silylations of aromatic substrates with base-activated organosilanes | TYR, DDC, TPST2 | ALDH1A1 1165/4885KDM4E 1154/4885HTT 3253/4885 |
| US-20210122701-A1 | SILYLATIONS OF AROMATIC SUBSTRATES WITH BASE-ACTIVATED ORGANOSILANES | TYR, DDC, TPST2 | ALDH1A1 1165/4885KDM4E 1154/4885HTT 3253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.