SCHEMBL8896871

SCHEMBL8896871

CN(C)C(C)(Cc1ccccc1Cl)C(=O)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.41
LMNA P02545 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
TAAR1 Q96RJ0 1/20 0.39
NR4A2 P43354 2/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
KCNJ6 P48051 1/20 0.39
KCNJ5 P48544 1/20 0.39
KCNJ3 P48549 1/20 0.39
ALDH1A1 P00352 1/20 0.38
CTBP2 P56545 1/20 0.38
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8897400 0.87 ALDH1A1 (0.41) KDM4ELMNASMN1; SMN2TAAR1NR4A2
SCHEMBL19601219 0.81 CYP1A2 (0.49) LMNAKMT2ANPC1RAB9AALDH1A1
SCHEMBL8899299 0.80 KMT2A (0.42) LMNASMN1; SMN2MEN1KMT2ATAAR1
SCHEMBL8896901 0.79 PPARG (0.46) LMNASMN1; SMN2MEN1KMT2ARAB9A
SCHEMBL8898280 0.75 NPC1 (0.44) LMNASMN1; SMN2MEN1KMT2ANPC1
SCHEMBL8897900 0.75 HPGD (0.47) SMN1; SMN2NPC1RAB9AALDH1A1
SCHEMBL3322033 0.75 HPGD (0.47) SMN1; SMN2NPC1RAB9AL3MBTL1ALDH1A1
SCHEMBL8897074 0.73 TDP1 (0.43) KDM4ELMNAMEN1KMT2ARAB9A
SCHEMBL8899384 0.73 GPR52 (0.40) KDM4ELMNASMN1; SMN2MEN1KMT2A
SCHEMBL8898504 0.71 ACHE (0.50) SMN1; SMN2MEN1KMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5629356-A PHOTOCURABLE COMPOSITION CONTAINING ETHYLENICALLY UNSATURATED PHOTOPOLYMERIZABLE COMPOUND AND THE AMINOACETOPHENONE CIBA GEIGY CORPORATION (US) 1997-05-13 US disclosed
US-5554663-A α-aminoacetophenones as photoinitiators CIBA-GEIGY CORPORATION (US) 1996-09-10 US disclosed
US-5534629-A PHOTOPOLYMERIZATION OF PIGMENTED SYSTEMS, INKS CIBA-GEIGY CORPORATION (US) 1996-07-09 US disclosed
EP-0284561-B1 ALPHA-AMINOACETOPHENONES AS PHOTO INITIATORS CIBA-GEIGY AG (CH) 1993-05-12 EP disclosed
US-5077402-A For photocuring pigmented systems; printing inks, lacquers CIBA-GEIGY CORPORATION (US) 1991-12-31 US disclosed
EP-0284561-A2 Alpha-aminoacetophenones as photo initiators CIBA-GEIGY AG (CH) 1988-09-28 EP disclosed