Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17707911 | 1.00 | TRPA1 (0.47) | TRPA1PTGS1CACNA1CALDH1A1ALOX12 | |
| SCHEMBL6399923 | 0.83 | ABCB11 (0.40) | TRPA1ALDH1A1HIF1AUGT2B7GAA | |
| SCHEMBL6403723 | 0.83 | TYR (0.49) | HIF1AUGT2B7GABRA1GABRB2SLC6A2 | |
| SCHEMBL22214043 | 0.82 | CYP1A2 (0.50) | TRPA1HIF1ALMNAGABRA1GABRB2 | |
| SCHEMBL10331781 | 0.82 | CYP1A2 (0.50) | TRPA1HIF1ALMNAGABRA1GABRB2 | |
| SCHEMBL16169461 | 0.80 | GABRA1 (0.50) | TRPA1PTGS1ALDH1A1HTTHIF1A | |
| SCHEMBL6400171 | 0.79 | GABRA1 (0.54) | TRPA1PTGS1ALDH1A1HTTHIF1A | |
| SCHEMBL23847834 | 0.79 | PTGS1 (0.46) | TRPA1PTGS1CACNA1CALDH1A1ALOX12 | |
| SCHEMBL28050435 | 0.79 | CYP2A6 (0.47) | TRPA1PTGS1ALDH1A1HIF1ALMNA | |
| Hydrogen Peroxide SCHEMBL9840257 | 0.79 | UGT2B7 (0.60) | TRPA1PTGS1CACNA1CALDH1A1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633418-A | CATALYTIC DIMERIZATION OF OLEFIN IN PRESENCE OF ORGANONICKEL, ORGANOALUMINUM AND ORGANOPHOSPHITE COMPOUNDS USED AS CATALYST | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-05-27 | — | — | US | disclosed |
| EP-0518241-B1 | Hydroformylation process and bisphosphite compound used therein | MITSUBISHI CHEM CORP (JP) | 1996-09-11 | — | — | EP | disclosed |
| US-5391801-A | Used to form respective aldehyde by reacting olefinic compound with carbon monoxide and hydrogen in presence of group 8 metal catalyst | MITSUBISHI KASEI CORPORATION (JP) | 1995-02-21 | — | — | US | disclosed |
| US-5235113-A | Reacting olefin with hydrogen and carbon monoxide in the presence of a group 8 metal catalyst and a phosphite compound | MITSUBISHI KASEI CORPORATION (JP) | 1993-08-10 | — | — | US | disclosed |
| EP-0518241-A2 | Hydroformylation process and bisphosphite compound used therein | Mitsubishi Chemical Corporation (JP) | 1992-12-16 | — | — | EP | disclosed |