Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | HTR2B | P41595 | 2/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6400171 | 0.96 | GABRA1 (0.54) | GABRA1GABRB2LMNASLC6A2HTR2B | |
| SCHEMBL10331781 | 0.82 | CYP1A2 (0.50) | GABRA1GABRB2LMNASLC6A2HTR2B | |
| SCHEMBL22214043 | 0.82 | CYP1A2 (0.50) | GABRA1GABRB2LMNASLC6A2HTR2B | |
| SCHEMBL24925045 | 0.81 | HTR2A (0.51) | HTR2BCYP1A2HTR2CALOX5 | |
| SCHEMBL8897330 | 0.80 | TRPA1 (0.47) | GABRA1GABRB2LMNASLC6A2HTR2B | |
| SCHEMBL17707911 | 0.80 | TRPA1 (0.47) | GABRA1GABRB2LMNASLC6A2HTR2B | |
| SCHEMBL6403723 | 0.79 | TYR (0.49) | GABRA1GABRB2SLC6A2UGT2B7CYP1A2 | |
| SCHEMBL29387216 | 0.79 | UGT2B7 (0.50) | GABRA1GABRB2LMNASLC6A2HTR2B | |
| SCHEMBL19997121 | 0.79 | GABRA1 (0.40) | GABRA1GABRB2LMNASLC6A2HTR2B | |
| SCHEMBL28050435 | 0.79 | CYP2A6 (0.47) | GABRA1GABRB2LMNASLC6A2HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9636656-B2 | Caged compound delivery and related compositions, methods and systems | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2017-05-02 | — | — | US | disclosed |
| US-20140311890-A1 | PHOTOACID COMPOUNDS, AND RELATED COMPOSITIONS, METHODS AND SYSTEMS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2014-10-23 | — | — | US | disclosed |
| US-20140308208-A1 | CAGED COMPOUND DELIVERY AND RELATED COMPOSITIONS, METHODS AND SYSTEMS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2014-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140308208-A1 | CAGED COMPOUND DELIVERY AND RELATED COMPOSITIONS, METHODS AND SYSTEMS | VIP, CRH, STRA6 | GABRA1 3153/4885GABRB2 2511/4885LMNA 816/4885 |
| US-20140311890-A1 | PHOTOACID COMPOUNDS, AND RELATED COMPOSITIONS, METHODS AND SYSTEMS | PAM, PPOX, HCCS | GABRA1 1807/4885GABRB2 2005/4885LMNA 1781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.