Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22214043 | 0.81 | CYP1A2 (0.50) | GABRA1LMNASLC6A2HTR2BTRPA1 | |
| SCHEMBL10331781 | 0.81 | CYP1A2 (0.50) | GABRA1LMNASLC6A2HTR2BTRPA1 | |
| SCHEMBL3143555 | 0.80 | CYP2A6 (0.56) | CYP2A6KDM4EMEN1MAPTKMT2A | |
| SCHEMBL17707911 | 0.79 | TRPA1 (0.47) | GABRA1LMNASLC6A2HTR2BTRPA1 | |
| SCHEMBL8897330 | 0.79 | TRPA1 (0.47) | GABRA1LMNASLC6A2HTR2BTRPA1 | |
| SCHEMBL16169461 | 0.79 | GABRA1 (0.50) | GABRA1GABRB1LMNASLC6A2HTR2B | |
| SCHEMBL282835 | 0.78 | GABRA1 (0.58) | GABRA1GABRB1LMNASLC6A2HTR2B | |
| SCHEMBL31182212 | 0.78 | GABRA1 (0.58) | GABRA1GABRB1LMNASLC6A2HTR2B | |
| SCHEMBL6400171 | 0.78 | GABRA1 (0.54) | GABRA1GABRB1LMNASLC6A2HTR2B | |
| SCHEMBL4912678 | 0.78 | LMNA (0.59) | GABRA1GABRB1LMNASLC6A2HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105272933-A | 5-naphthyl-2-amino-benzo[d]oxazole derivative, preparation method and uses thereof | ZHANG HAO | 2016-01-27 | — | — | CN | claimed |
| CN-105272933-A | 5-naphthyl-2-amino-benzo[d]oxazole derivative, preparation method and uses thereof | ZHANG HAO | 2016-01-27 | — | — | CN | disclosed |