Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 3/20 | 0.35 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4140768 | 0.93 | TSHR (0.42) | LMNAALDH1A1TSHRCYP1A2MEN1 | |
| SCHEMBL23810051 | 0.93 | TSHR (0.48) | LMNAMAPTMAPK1ALDH1A1TSHR | |
| SCHEMBL6379709 | 0.89 | TSHR (0.47) | LMNATSHRMMP1MMP2MMP3 | |
| SCHEMBL23810012 | 0.89 | TSHR (0.54) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL23810076 | 0.86 | ALDH1A1 (0.43) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL20998589 | 0.86 | KISS1R (0.47) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL23059561 | 0.84 | LMNA (0.35) | LMNAMAPTMAPK1ALDH1A1TSHR | |
| SCHEMBL6379703 | 0.84 | EGLN1 (0.39) | LMNAALDH1A1MMP1MMP2MMP3 | |
| SCHEMBL23814197 | 0.81 | MMP1 (0.35) | LMNAALDH1A1PRKCATSHRMMP1 | |
| SCHEMBL3765880 | 0.80 | LMNA (0.52) | LMNAMAPTMAPK1ALDH1A1PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5702709-A | CONTAINING ORGANOPHILIC CLAY | ENVIRODERM PHARMACEUTICALS, INC. (US) | 1997-12-30 | — | — | US | claimed |