SCHEMBL16409145

SCHEMBL16409145

COCC(C)(COC)C(C)=O

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.37
ALDH1A1 P00352 1/20 0.33
MGAM O43451 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
CYP2D6 P10635 1/20 0.31
TSHR P16473 1/20 0.31
CYP2C19 P33261 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12141355 0.87 GAA (0.33) GAAALDH1A1TSHR
SCHEMBL19999961 0.87 GAA (0.33) GAA
SCHEMBL889792 0.78 TSHR (0.48) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
SCHEMBL8290885 0.78
SCHEMBL2031592 0.78 DGAT1 (0.42) GAAALDH1A1MGAMSIMGAM2
SCHEMBL13798085 0.76 MCL1 (0.33) ALDH1A1
SCHEMBL13615363 0.76 ALDH1A1 (0.43) GAAALDH1A1TSHR
SCHEMBL16155106 0.76
SCHEMBL20783127 0.76 LMNA (0.35) ALDH1A1CYP2C19
SCHEMBL12733050 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230330134-A1 METHOD OF PROPHYLAXIS OF CORONAVIRUS AND/OR RESPIRATORY SYNCYTIAL VIRUS INFECTION STARPHARMA PTY LTD. (AU) 2023-10-19 US disclosed
US-20180090787-A1 SOLID ELECTROLYTE COMPOSITION, ELECTRODE SHEET FOR ALL-SOLID STATE SECONDARY BATTERY, ALL-SOLID STATE SECONDARY BATTERY, AND METHODS FOR MANUFACTURING ELECTRODE SHEET FOR ALL-SOLID STATE SECONDARY BATTERY AND ALL-SOLID STATE SECONDARY BATTERY FUJIFILM CORPORATION (JP) 2018-03-29 US disclosed
US-9770439-B2 Hepatitis C virus inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2017-09-26 US disclosed
US-20160158200-A1 Combinations of Hepatitis C Virus Inhibitors BRISTOL MYERS SQUIBB CO (US) 2016-06-09 US disclosed
US-20150297568-A1 Hepatitis C Virus Inhibitors BRISTOL MYERS SQUIBB CO (US) 2015-10-22 US disclosed
US-20150238557-A1 METHOD OF TREATMENT OR PROPHYLAXIS OF INFECTIONS OF THE EYE STARPHARMA PTY LIMITED (AU) 2015-08-27 US disclosed
US-9051336-B2 Regioselective acylation of rapamycin at the C-42 position SANDOZ (CH) 2015-06-09 US disclosed
US-20150023913-A1 Hepatitis C Virus Inhibitors BRISTOL-MYERS SQUIBB COMPANY 2015-01-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230330134-A1 METHOD OF PROPHYLAXIS OF CORONAVIRUS AND/OR RESPIRATORY SYNCYTIAL VIRUS INFECTION SARS1, ACE, ACE2 GAA 1775/4885ALDH1A1 2637/4885MGAM 518/4885
US-20150238557-A1 METHOD OF TREATMENT OR PROPHYLAXIS OF INFECTIONS OF THE EYE TLR9, TLR1, TLR3 GAA 1126/4885ALDH1A1 1418/4885MGAM 64/4885
US-20150023913-A1 Hepatitis C Virus Inhibitors HAVCR2, MAVS, EIF2AK2 GAA 931/4885ALDH1A1 3966/4885MGAM 3619/4885
US-20150297568-A1 Hepatitis C Virus Inhibitors HAVCR2, MAVS, EIF2AK2 GAA 931/4885ALDH1A1 3966/4885MGAM 3619/4885
US-20160158200-A1 Combinations of Hepatitis C Virus Inhibitors HAVCR2, EIF2AK2, MAVS GAA 1244/4885ALDH1A1 3872/4885MGAM 3810/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.