Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | CCR2 | P41597 | 2/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PPOX | P50336 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8895085 | 0.81 | PPOX (0.54) | TSHRMAPK1RECQLALDH1A1MAPT | |
| SCHEMBL8896586 | 0.79 | PPOX (0.49) | TSHRL3MBTL1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL17542785 | 0.75 | ALDH1A1 (0.56) | TSHRALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL29948657 | 0.75 | ALDH1A1 (0.56) | TSHRALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL9727445 | 0.67 | TSHR (0.55) | TSHRMAPK1RECQLALDH1A1SMN1; SMN2 | |
| SCHEMBL6393297 | 0.67 | CCR2 (0.67) | CCR2CCR1CCR5 | |
| SCHEMBL6393300 | 0.67 | CCR2 (0.67) | CCR2CCR1CCR5 | |
| SCHEMBL17542826 | 0.67 | LGMN (0.59) | TSHRALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL3436573 | 0.66 | MEN1 (0.61) | TSHRALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL11038098 | 0.66 | AR (0.52) | CCR2CCR1CCR5L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643855-A | Herbicidal imidazolones | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-07-01 | — | — | US | disclosed |
| EP-0674644-A1 | HERBICIDAL IMIDAZOLONES AND A PROCESS FOR THEIR MANUFACTURE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994014817-A1 | HERBICIDAL IMIDAZOLONES AND A PROCESS FOR THEIR MANUFACTURE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-07-07 | — | — | WO | disclosed |