SCHEMBL8897989

SCHEMBL8897989

C=CCC(CC=C)(C(=O)c1ccc(N(C)C)cc1)N(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.46
ALDH1A1 P00352 4/20 0.46
HPGD P15428 3/20 0.46
RAB9A P51151 4/20 0.41
NPC1 O15118 4/20 0.41
HDAC1 Q13547 5/20 0.39
HDAC6 Q9UBN7 5/20 0.39
KMT2A Q03164 4/20 0.39
MEN1 O00255 3/20 0.39
POLB P06746 2/20 0.38
GAA P10253 2/20 0.38
KDM4E B2RXH2 1/20 0.38
MAPK1 P28482 1/20 0.38
ALOX15 P16050 1/20 0.38
HSD17B10 Q99714 1/20 0.38
HDAC3 O15379 3/20 0.38
HDAC4 P56524 3/20 0.38
HDAC7 Q8WUI4 3/20 0.38
HDAC2 Q92769 3/20 0.38
HDAC10 Q969S8 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8898163 0.87 KMT2A (0.47) MAPTALDH1A1HPGDRAB9ANPC1
SCHEMBL8898410 0.84 CYP1A2 (0.41) MAPTRAB9ANPC1SMN1; SMN2
SCHEMBL8898133 0.84 TSHR (0.45) MAPTALDH1A1HPGDRAB9ANPC1
SCHEMBL8899809 0.83 MAPT (0.44) MAPTALDH1A1HPGDRAB9ANPC1
SCHEMBL8898996 0.82 ALDH1A1 (0.40) MAPTALDH1A1RAB9ANPC1KMT2A
SCHEMBL8898339 0.82 PKM (0.49) MAPTALDH1A1HPGDHDAC1HDAC6
SCHEMBL8898900 0.81 RAB9A (0.43) MAPTALDH1A1HPGDRAB9ANPC1
SCHEMBL8897547 0.79 SMN1; SMN2 (0.48) ALDH1A1HPGDRAB9ANPC1KMT2A
SCHEMBL3428089 0.78 L3MBTL1 (0.40) SMN1; SMN2
SCHEMBL13310001 0.78 EGFR (0.34) ALDH1A1HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5698285-A PHOTOCURABLE THREE BOND CO., LTD. (JP) 1997-12-16 US disclosed
US-5629356-A PHOTOCURABLE COMPOSITION CONTAINING ETHYLENICALLY UNSATURATED PHOTOPOLYMERIZABLE COMPOUND AND THE AMINOACETOPHENONE CIBA GEIGY CORPORATION (US) 1997-05-13 US disclosed
US-5554663-A α-aminoacetophenones as photoinitiators CIBA-GEIGY CORPORATION (US) 1996-09-10 US disclosed
US-5534629-A PHOTOPOLYMERIZATION OF PIGMENTED SYSTEMS, INKS CIBA-GEIGY CORPORATION (US) 1996-07-09 US disclosed
EP-0284561-B1 ALPHA-AMINOACETOPHENONES AS PHOTO INITIATORS CIBA-GEIGY AG (CH) 1993-05-12 EP disclosed
US-5077402-A For photocuring pigmented systems; printing inks, lacquers CIBA-GEIGY CORPORATION (US) 1991-12-31 US disclosed
EP-0284561-A2 Alpha-aminoacetophenones as photo initiators CIBA-GEIGY AG (CH) 1988-09-28 EP disclosed