Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6026322 | 0.85 | CYP1A2 (0.41) | MAPTRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL8898434 | 0.84 | TSHR (0.44) | MAPTALDH1A1RAB9ANPC1KMT2A | |
| SCHEMBL8897989 | 0.83 | MAPT (0.46) | MAPTALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL8897630 | 0.83 | HDAC3 (0.41) | MAPTALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL8898143 | 0.82 | ALDH1A1 (0.42) | MAPTALDH1A1RAB9ANPC1KMT2A | |
| SCHEMBL9679522 | 0.82 | ALDH1A1 (0.52) | MAPTALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL9679885 | 0.78 | ALDH1A1 (0.47) | MAPTALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL3432893 | 0.78 | LMNA (0.33) | MAPTALDH1A1RAB9AKMT2AMEN1 | |
| SCHEMBL4650902 | 0.76 | GSK3B (0.46) | MAPTALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL8899686 | 0.76 | ALDH1A1 (0.44) | MAPTALDH1A1HPGDRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629356-A | PHOTOCURABLE COMPOSITION CONTAINING ETHYLENICALLY UNSATURATED PHOTOPOLYMERIZABLE COMPOUND AND THE AMINOACETOPHENONE | CIBA GEIGY CORPORATION (US) | 1997-05-13 | — | — | US | disclosed |
| US-5554663-A | α-aminoacetophenones as photoinitiators | CIBA-GEIGY CORPORATION (US) | 1996-09-10 | — | — | US | disclosed |
| US-5534629-A | PHOTOPOLYMERIZATION OF PIGMENTED SYSTEMS, INKS | CIBA-GEIGY CORPORATION (US) | 1996-07-09 | — | — | US | disclosed |
| EP-0284561-B1 | ALPHA-AMINOACETOPHENONES AS PHOTO INITIATORS | CIBA-GEIGY AG (CH) | 1993-05-12 | — | — | EP | disclosed |
| US-5077402-A | For photocuring pigmented systems; printing inks, lacquers | CIBA-GEIGY CORPORATION (US) | 1991-12-31 | — | — | US | disclosed |
| EP-0284561-A2 | Alpha-aminoacetophenones as photo initiators | CIBA-GEIGY AG (CH) | 1988-09-28 | — | — | EP | disclosed |