Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 10/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 10/20 | 0.55 |
| ▸ | USP2 | O75604 | 6/20 | 0.55 |
| ▸ | CLK4 | Q9HAZ1 | 6/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.55 |
| ▸ | TOP2A | P11388 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8898746 | 0.90 | TOP2A (0.53) | CYP1A2CYP3A4CYP2D6USP2CLK4 | |
| SCHEMBL8890645 | 0.89 | TLR9 (0.47) | CYP1A2CYP3A4CYP2D6USP2CLK4 | |
| SCHEMBL8901507 | 0.88 | TRIM58 (0.53) | CYP1A2CYP3A4CYP2D6USP2CLK4 | |
| SCHEMBL8898079 | 0.88 | ACP1 (0.54) | CYP1A2CYP3A4CYP2D6USP2CLK4 | |
| SCHEMBL13796629 | 0.85 | ALDH1A1 (0.58) | CYP1A2CYP3A4CYP2D6USP2CLK4 | |
| SCHEMBL8898278 | 0.83 | SOS1 (0.52) | KMT2ALMNAMAPTALDH1A1TDP1 | |
| SCHEMBL13796818 | 0.82 | NPY5R (0.65) | CYP1A2CYP3A4CYP2D6USP2CLK4 | |
| SCHEMBL14606893 | 0.82 | ALDH1A1 (0.52) | CYP1A2CYP3A4CYP2D6USP2CLK4 | |
| SCHEMBL13796639 | 0.82 | MAPT (0.56) | CYP1A2CYP3A4CYP2D6USP2CLK4 | |
| SCHEMBL13795436 | 0.82 | NPY5R (0.57) | CYP1A2CYP3A4CYP2D6USP2CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |