Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 9/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 9/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 5/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8898730 | 0.91 | ACP1 (0.52) | ACP1TOP2A | |
| SCHEMBL8890605 | 0.90 | VCP (0.44) | ACP1USP2TLR9 | |
| SCHEMBL8901492 | 0.89 | TRIM58 (0.49) | ACP1 | |
| SCHEMBL8898099 | 0.88 | CYP1A2 (0.55) | ACP1CYP1A2CYP3A4CYP2D6ALOX15 | |
| SCHEMBL8901739 | 0.84 | TAAR1 (0.52) | KMT2AMAPTALDH1A1POLB | |
| SCHEMBL8898260 | 0.84 | VCP (0.50) | — | |
| SCHEMBL13796629 | 0.83 | ALDH1A1 (0.58) | ACP1CYP1A2CYP3A4CYP2D6ALOX15 | |
| SCHEMBL8900663 | 0.82 | LRRK2 (0.56) | ALOX15TSHRHSD17B10LMNAMAPT | |
| SCHEMBL8898351 | 0.81 | VCP (0.48) | CYP1A2CYP3A4ALOX15CLK4HSD17B10 | |
| SCHEMBL8890197 | 0.81 | PDE5A (0.48) | ACP1POLBTOP2ATLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |